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Tablets, film-coated white, slightly biconvex, tear-shaped, with beveled, engraved with "20" on one side, smooth on the other side. The main component of the substance rimonabant, is contained in the tablet 20 mg. Excipients: corn starch, lactose monohydrate, povidone K30, croscarmellose sodium, sodium lauryl sulfate, microcrystalline cellulose (90 microns), magnesium stearate, hypromellose (15 mPa.s), titanium dioxide, macrogol 3000, carnauba wax.

Symptoms: up to date information on cases of intentional overdose have been reported. Doses of 80 mg / day were well tolerated by patients. Treatment: specific antidote is known. Rabeprazole is well bound to plasma proteins, and therefore not displayed by dialysis. Recommended holding symptomatic and supportive treatment.

The recommended dose for adults is 20 mg / day (1 tablet) in the morning before breakfast. The patient should be warned about the need for strict compliance with the designated dose. Treatment should be started simultaneously with moderate low-calorie diet. Duration of treatment drug Acomplia establishes doctor. Safety and efficacy of rimonabant beyond 2 years of not studying.

In placebo-controlled studies the frequency of discontinuation of treatment with rimonabant due to adverse reactions was 15.7%. The most common adverse reactions that have led to discontinuation of treatment were nausea, mood changes with depressive symptoms, depressive disorders, anxiety and dizziness. Depressive disorders observed in 3.2% of patients with obesity or overweight with associated risk factors, which are used rimonabant 20 mg. These violations were weak or moderate. In all cases, recovery occurred as a result of corrective treatment or after discontinuation of rimonabant, and there were no differences compared with cases that are noted in the control groups.

Experience of overdose rimonabant is limited. In a single dose tolerability study of a limited number of patients used doses up to 300 mg. This marked only marginally severe symptoms: headache, euphoria, fatigue and insomnia.
Rimonabant no specific antidote exists, so in case of overdose should conduct appropriate supportive treatment. It should consist of general activities that are used in overdose, such as ensuring the airway, control functions of the cardiovascular system and general symptomatic and supportive therapy.