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Issued in coated tablets soluble in the intestine. Main ingredient rabeprazole sodium. Excipients: mannitol (mannitol), magnesium oxide, hydroxypropylcellulose slabozameschennaya (giproloza slabozameschennaya), hydroxypropylcellulose (giproloza), magnesium stearate, ethylcellulose, hypromellose phthalate, diatsetilirovanny monoglyceride, talc, titanium dioxide, iron oxide yellow (tablets of 20 mg), iron oxide red (in tablets of 10 mg), ethanol (evaporates during the manufacturing process), Purified Water (evaporates during the manufacturing process), carnauba wax, edible gray ink F6 (tablets of 10 mg), edible red ink A1 (tablets 20 mg), 1-Butanol (evaporates during the manufacturing process).

Duodenal ulcer in the acute stage, stomach ulcer in the acute stage, gastroesophageal reflux disease, erosive reflux, esophagitis (treatment), symptomatic treatment neerozivnoy reflux disease, Zollinger-Ellison syndrome or other conditions characterized by pathological hypersecretion. In combination with antibacterial agents used in the following states: eradication of Helicobacter pylori in patients with gastric ulcer or chronic gastritis, treatment and prevention of recurrence of ulcers in patients with peptic ulcer disease associated with Helicobacter pylori.

Inside, not liquid and not crushed, swallowing whole.
When duodenal ulcer and gastric ulcer in the acute stage is recommended to ingest at one table. (20 mg) once daily in the morning for 4-6 weeks.
Patients with gastroesophageal reflux disease are advised to take one table. 20 mg once a day for 4-8 weeks.
For treatment of Zollinger-Ellison syndrome and other conditions characterized by pathological hypersecretion, the dose picked individually. Initial dose - 60 mg per day, then it increases and prescribe medication in a dose of 100 mg per day with a single dose or 60 mg 2 times a day. For some patients, a fraction lower dose is preferred. Treatment should continue for at least a clinical need. Some patients with Zollinger-Ellison syndrome rabeprazole treatment duration was up to one year.
For the treatment of duodenal ulcer or chronic gastritis associated with infection Helicobacter pylori, using several variants of eradication using appropriate combinations of antibiotics.

Based on the experience of clinical trials, we can conclude that Aciphex is generally well tolerated by patients. Side effects in general, weakly expressed or moderate and were transient in nature. When you receive a product Aciphex noted the following side effects: headache, diarrhea, abdominal pain, asthenia, flatulence, skin rashes and dry mouth. In rare cases reported allergic reactions (swelling of the face, dyspnea, erythema or bullous rashes) in patients taking Aciphex. These reactions usually disappear with discontinuation. Also, in rare cases, there were thrombocytopenia, neutropenia and leukopenia, leukocytosis, anorexia.
Instances were noted increasing levels of liver enzymes. Communication with taking this medication has not been established: back pain, flu syndrome, myalgia, arthralgia, rarely - decreased appetite, weight gain, depression, blurred vision or taste, stomatitis, increased sweating.

Symptoms: up to date information on cases of intentional overdose have been reported. Doses of 80 mg / day were well tolerated by patients. Treatment: specific antidote is known. Rabeprazole is well bound to plasma proteins, and therefore not displayed by dialysis. Recommended holding symptomatic and supportive treatment.